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Ritonavir or lopinavir/ritonavir tremendously boost plasma concentrations of oxycodone in wholesome human volunteers as a consequence of inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin enormously decreases plasma concentrations of oxycodone as a consequence of powerful induction of CYP3A4.We only use high-quality, credible sources to ensur